MARKETING ANALYSIS OF THE ASSORTMENT OF DRUGS FOR THE TREATMENT OF HERPES VIRAL DISEASES AT THE PHARMACEUTICAL MARKET OF UKRAINE
Abstract
Nowadays there is a tendency towards the spread of viral diseases that cause significant complications to human health. Therefore, the question of creating new drugs that have a high antiviral effect is topical.
The aim. To study the range of drugs in Ukraine for the treatment of herpes viral diseases.
Materials and methods. In the work were used the list of drugs from official sources of information, which were processed by methods of generalization, systematization, graphic, comparative and structural analysis.
Results and discussion. The marketing research of drugs for the treatment of herpes viral diseases presented at the pharmaceutical market of Ukraine has been conducted. According to the results it is found that 80 drugs for the treatment of herpes viral diseases of various dosage forms are presented in the domestic market, of which 70 % – tablets; 51 % – medicines produced by the industry of Ukraine; 94 % – are monocomponent preparations.
Soft drugs play important role in the treatment of skin diseases because they provide a direct effect of the drugs on the pathogens, eliminate inflammatory phenomena and eliminate or reduce the symptoms of the disease. Soft dosage drugs have practically no contraindications, they can be used at any age, regardless of the presence of comorbidities.
Conclusions. Domestic drugs (51 % of the total range) dominate in the market structure. The main part (94 %) consist of monocomponent preparations. The results of the research prove the relevance of the development of new combined soft dosage forms for the treatment of herpes viral diseases, which should be produced by the Ukrainian industry and satisfy the medical and economical needs of patients. The results of the marketing analysis show that it is relevant and promising to create new combined the soft dosage forms for the treatment of herpes viral diseases.
Downloads
References
Ruderfer, D., Krilov, L. R. (2015). Herpes Simplex Viruses 1 and 2. Pediatrics in Review, 36 (2), 86–90. doi: http://doi.org/10.1542/pir.36-2-86
Kinchington, P. R., Leger, A. J. S., Guedon, J.-M. G., Hendricks, R. L. (2012). Herpes simplex virus and varicella zoster virus, the house guests who never leave. Herpesviridae, 3 (1), 1–13. doi: http://doi.org/10.1186/2042-4280-3-5
Mustafa, M., Illzam, E., Muniandy, R., Sharifah, A., Nang, M., Ramesh, B. (2016). Herpes simplex virus infections, Pathophysiology and Management. IOSR Journal of Dental and Medical Sciences, 15 (7), 85–91. doi: http://doi.org/10.9790/0853-150738591
Suzich, J. B., Cliffe, A. R. (2018). Strength in diversity: Understanding the pathways to herpes simplex virus reactivation. Virology, 522, 81–91. doi: http://doi.org/10.1016/j.virol.2018.07.011
El Hayderi, L., Delvenne, P., Rompen, E., Senterre, J. M., Nikkels, A. F. (2013). Herpes simplex virus reactivation and dental procedures. Clinical Oral Investigations, 17 (8), 1961–1964. doi: http://doi.org/10.1007/s00784-013-0986-3
Williams, E. J., Embleton, N. D., Clark, J. E., Bythell, M., Ward Platt, M. P., Berrington, J. E. (2013). Viral Infections: Contributions to Late Fetal Death, Stillbirth, and Infant Death. The Journal of Pediatrics, 163 (2), 424–428. doi: http://doi.org/10.1016/j.jpeds.2013.02.004
Egan, K. P., Wu, S., Wigdahl, B., Jennings, S. R. (2013). Immunological control of herpes simplex virus infections. Journal of NeuroVirology, 19 (4), 328–345. doi: http://doi.org/10.1007/s13365-013-0189-3
Stephenson-Famy, A., Gardella, C. (2014). Herpes Simplex Virus Infection During Pregnancy. Obstetrics and Gynecology Clinics of North America, 41 (4), 601–614. doi: http://doi.org/10.1016/j.ogc.2014.08.006
Torres, L., Ortiz, T., Tang, Q. (2015). Enhancement of Herpes Simplex Virus (HSV) Infection by Seminal Plasma and Semen Amyloids Implicates a New Target for the Prevention of HSV Infection. Viruses, 7 (4), 2057–2073. doi: http://doi.org/10.3390/v7042057
Roizman, B., Whitley, R. J. (2013). An Inquiry into the Molecular Basis of HSV Latency and Reactivation. Annual Review of Microbiology, 67 (1), 355–374. doi: http://doi.org/10.1146/annurev-micro-092412-155654
Piret, J., Boivin, G. (2010). Resistance of Herpes Simplex Viruses to Nucleoside Analogues: Mechanisms, Prevalence, and Management. Antimicrobial Agents and Chemotherapy, 55 (2), 459–472. doi: http://doi.org/10.1128/aac.00615-10
Bhalekar, M., Upadhaya, P., Reddy, S., Kshirsagar, S., Madgulkar, A. (2014). Formulation and evaluation of acyclovir nanosuspension for enhancement of oral bioavailability. Asian Journal of Pharmaceutics, 8 (2), 110–118. doi: http://doi.org/10.4103/0973-8398.134942
Kawamura, K., Hayakawa, J., Akahoshi, Y., Harada, N., Nakano, H., Kameda, K. et. al. (2015). Low-dose acyclovir prophylaxis for the prevention of herpes simplex virus and varicella zoster virus diseases after autologous hematopoietic stem cell transplantation. International Journal of Hematology, 102 (2), 230–237. doi: http://doi.org/10.1007/s12185-015-1810-4
Popova, O. I. (2013). Herpetychna infektsiia yak providna medyko-sotsialna problema. Sovremennaia stomatolohyia, 2, 48–50.
Bardova, E. A. (2011). Gerpeticheskaia infektsiia: patogenez, klinika, lechenie. Medix Anti – Agent, 2 (20), 44–50.
Kennedy, P. G. E., Rovnak, J., Badani, H., Cohrs, R. J. (2015). A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation. Journal of General Virology, 96 (7), 1581–1602. doi: http://doi.org/10.1099/vir.0.000128
Levachkova, Yu. V., Yarnykh, T. G., Litvinova, O. M. (2014). Antiviras today and the prospects of development in Ukraine. Ukrainian biopharmaceutical journal, 6 (35), 18–22.
Aslanyan, M., Bobrуtska, L., Hrytsenko, V., Shpychak, O., Popova, N., Germanyuk, T. et. al. (2017). Technological aspects of development of a new drug in tablets called «Lavaflam» and its pharmacoeconomic evaluation. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 4 (8), 808–814.
Looker, K. J., Magaret, A. S., May, M. T., Turner, K. M. E., Vickerman, P., Gottlieb, S. L., Newman, L. M. (2015). Global and Regional Estimates of Prevalent and Incident Herpes Simplex Virus Type 1 Infections in 2012. PLOS ONE, 10 (10), 1–10. doi: http://doi.org/10.1371/journal.pone.0140765
Kovalenko, V. N. (Ed.) (2015). Kompendium 2015 – lekarstvennye preparaty. Kyiv: Morion, 2320.
Bobrytska, L. O., Ruban, O. A., Puliaiev, D. S. (2012). Osoblyvosti perebihu ta aspekty farmakoterapii herpesvirusnoi infektsii. Zbiórraportównaukowych. «Postępy w nauce w ostatnichlatach. Nowychrozwiązań», 9, 29–31.
Copyright (c) 2020 Lydmila Kienko, Vita Hrytsenko, Larysa Iakovlieva, Larysa Bobrytska
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the CREATIVE COMMONS copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons Attribution License, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
