The effect of the drug "Cobazin" on the productive indicators of bee colonies

Keywords: Cobazin, bee colony, stimulants, colony strength, bee, productivity, health productivity, cobalt, germanium, zinc, immunostimulant, honey, queen bee, brood

Abstract

The aim of the study was to determine the effectiveness of the drug "Cobazin" on the productivity of bee colonies during the increase in strength (increase in the number of young bees in the bee colony) in spring and autumn.

Materials and methods. Control and experimental groups were formed to test "Cobazin" feed supplement. It was fed 5 times with an interval of 5 days. Bee colonies from the control group received a pure sugar solution (1:1) in the amount of 0.5 liters per bee colony, and the experimental group received a sugar solution of 0.5 liters per bee colony (1:1) with the addition of the drug "Cobazin" in the amount of 2.5 g.

Indicators characterizing the development of bee colonies were determined by a measuring frame of 5x5 cm in size, for 12 days to cover the total number of eggs laid by the queen bee during feeding. Four measurements were performed during the study. The results of the control and experimental groups were compared and the significance of the differences between them was established. There was a comparison of the difference between groups of bees both fed pure sugar syrup in a ratio of 1:1 and syrup with the addition of the drug "Cobazin".

Results. It is proved that during the feeding period the number of brood in bee colonies that received feed supplement "Cobazin" increased significantly by 76 % (71 % in the group that received only sugar solution without this drug). Live weight of queen bees in colonies that were stimulated with "Cobazin" was actually 2 % higher compared to the control group.

It was found that at the end of the bee season, bee colonies fed in May with the feed supplement "Cobazin" had significantly higher values of strength, number of sealed brood and live queen bees compared to those who received pure sugar solution. The brood in the control group was 25 % lower than in the experimental group.

Conclusions. For the first time it was proved that the use of feed supplement "Cobazin" in combination with sugar solution has a positive effect on the features that characterize the development of bee colonies (strength, number of sealed brood) and their health productivity. The positive impact is observed not only during feeding, but also in subsequent periods of colony development.

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Author Biographies

Dmytro Kisil, Sumy National Agrarian University

Department of Veterinary Examination, Microbiology, Zoohygiene and Safety and Quality of Livestock Products

Tetiana Fotina, Sumy National Agrarian University

Department of Veterinary Examination, Microbiology, Zoohygiene and Safety and Quality of Livestock Products

Svitlana Nazarenko, Sumy National Agrarian University

Department of Veterinary Examination, Microbiology, Zoohygiene and Safety and Quality of Livestock Products

References

Musiyenko, O. V., Kysterna, O. S. (2017). Putrefactive diseases of bees, features of diagnosis and control. Bulletin of Sumy National Agrarian University. Series: Veterinary Medicine, 11 (1), 90–95.

Kisil, D. O., Fotina, T. I. (2018). Monitoring the epizoetic situation on mixed infectious diseases in bees in Northern Eastern region of Ukraine. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies, 20 (83), 381–384. doi: http://doi.org/10.15421/nvlvet8375

Neumann, P., Elzen, P. J. (2004). The biology of the small hive beetle (Aethina tumida, Coleoptera: Nitidulidae): Gaps in our knowledge of an invasive species. Apidologie, 35 (3), 229–247. doi: http://doi.org/10.1051/apido:2004010

Berezovsky, A. (2012). Nosematosis is a problematic disease of bee colonies. Ukrainian beekeeper, 9, 22–24.

Ao, Y., Chen, J., Yue, J., Peng, R.-X. (2008). Effects of 18α-glycyrrhizin on the pharmacodynamics and pharmacokinetics of glibenclamide in alloxan-induced diabetic rats. European Journal of Pharmacology, 587 (1-3), 330–335. doi: http://doi.org/10.1016/j.ejphar.2008.03.043

Puente, J., Gascon, F., Ponte, B., de la Fuente, D. (2019). On strategic choices faced by large pharmaceutical laboratories and their effect on innovation risk under fuzzy conditions. Artificial Intelligence in Medicine, 100, 101703. doi: http://doi.org/10.1016/j.artmed.2019.101703

Lim, W., Chia, Y., Liong, S., Ton, S., Kadir, K., Syed Husain, S. (2009). Lipoprotein lipase expression, serum lipid and tissue lipid deposition in orally-administered glycyrrhizic acid-treated rats. Lipids in Health and Disease, 8 (1), 31. doi: http://doi.org/10.1186/1476-511x-8-31

Fox, N. J., Ward, K. J. (2008). Pharma in the bedroom … and the kitchen … The pharmaceuticalisation of daily life. Sociology of Health & Illness, 30 (6), 856–868. doi: http://doi.org/10.1111/j.1467-9566.2008.01114.x

Koga, K., Kawashima, S., Shibata, N., Takada, K. (2007). Novel Formulations of a Liver Protection Drug Glycyrrhizin. Yakugaku Zasshi, 127 (7), 1103–1114. doi: http://doi.org/10.1248/yakushi.127.1103

Hanje, A. J., Fortune, B., Song, M., Hill, D., McClain, C. (2006). The Use of Selected Nutrition Supplements and Complementary and Alternative Medicine in Liver Disease. Nutrition in Clinical Practice, 21 (3), 255–272. doi: http://doi.org/10.1177/0115426506021003255

Lu, L. G., Xu, H. J., Wang, Y. J. (2005). Therapeutic effect of diammonium glycyrrhizinate lipid ligand on carbon-tetrarchloride induced fatty livers in rats. Zhonghua Gan Zang Bing Za Zhi, 10, 786–788.

Tripathi, M., Singh, B. K., Kakkar, P. (2009). Glycyrrhizic acid modulates t-BHP induced apoptosis in primary rat hepatocytes. Food and Chemical Toxicology, 47 (2), 339–347. doi: http://doi.org/10.1016/j.fct.2008.11.028

Kisil, D. O. (2019). Determination of veterinary - sanitary assessment of honey and its level of toxicity after the application of food additive "Кoвacin" for stimulation the power of beees families and comparative safety assessment with other analoges. Scientific and Technical Bulletin of the Institute of Veterinary Drugs and Feed Additives Institute of Animal Biology, 20 (2), 311–316. doi: http://doi.org/10.36359/scivp.2019-20-2.40

Sirenko, O. S., Desyatnikova, O. V., Gurieva, V. B. (2019). Effectiveness of the “Guanidez” disinfectant on the agents of bee infectious diseases in laboratory conditions. Veterinary Medicine: Inter-Departmental Subject Scientific Collection, 105 (1), 59–62. doi: http://doi.org/10.36016/vm-2019-105-11

Kysterna, O. S., Harkava, V. V., Musiienko, O. V. (2014). Features of preparation of smears of hemolymph of an imago bee. The Animal Biology, 16 (4), 118.

Danihlík, J., Aronstein, K., Petřivalský, M. (2015). Antimicrobial peptides: a key component of honey bee innate immunity. Journal of Apicultural Research, 54 (2), 123–136. doi: http://doi.org/10.1080/00218839.2015.1109919

Gatschenberger, H., Gimple, O., Tautz, J., Beier, H. (2012). Honey bee drones maintain humoral immune competence throughout all life stages in the absence of vitellogenin production. Journal of Experimental Biology, 215 (8), 1313–1322. doi: http://doi.org/10.1242/jeb.065276

Vedmed, I. V., Sheremeta, V. I., Kaplunenko, V. G. (2018). Melliferous capacity of bee families depending on the quality of queen bees, derived with using of biologically active feeding. Animal Breeding and Genetics, 51, 296–302. doi: http://doi.org/10.31073/abg.51.40

El Mohandes, S., Nafea, E., Fawzy, A. (2010). Effect of different feeding diets on the haemolymph of the newly emerged honeybee workers Apis mellifera L. Egyptian Academic Journal of Biological Sciences. A, Entomology, 3 (1), 113–220. doi: http://doi.org/10.21608/eajbsa.2010.15257

Richardson, R. T., Ballinger, M. N., Qian, F., Christman, J. W., Johnson, R. M. (2018). Morphological and functional characterization of honey bee, Apis mellifera, hemocyte cell communities. Apidologie, 49 (3), 397–410. doi: http://doi.org/10.1007/s13592-018-0566-2


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Published
2021-03-31
How to Cite
Kisil, D., Fotina, T., & Nazarenko, S. (2021). The effect of the drug "Cobazin" on the productive indicators of bee colonies. EUREKA: Health Sciences, (2), 90-96. https://doi.org/10.21303/2504-5679.2021.001711
Section
Veterinary Science and Veterinary Medicine