THE FEATURES OF ACUTE BRUCELLOSIS IN AZERBAIJAN REPUBLIC

  • Elchin Mammad oglu Huseynov Azerbaijan Medical University
Keywords: acute brucellosis, interleukin-4, interleukin-6, toll-like receptors, immunoglobulin

Abstract

It is well known, that the injury of organs and systems and also immunological rates considerably determine clinical course and the result of brucellosis. In the article are presented the results of examination of 120 patients with acute brucellosis. The control group included 30 practically healthy persons. Groups were representative by the age and sex. The diagnosis of brucellosis was set on the base of complaints, anamnesis, epidemiological and clinical data and the results of serological examination of the blood. All patients also underwent the fixation of interleukin -6, іinterleukin-4 and TLR-2 in the blood serum. The detailed epidemiological, clinical and immunological characteristic of patients with brucellosis was presented. Among examined persons prevailed men, persons of young able-bodied persons and rural dwellers. It was revealed, that the dominating way of transmission was the contact one. The highest level of infection was fixed among the workers of farm enterprises and veterinarians. The season features were also revealed, the highest level of morbidity was in summer-autumn period. The main clinical features were: fever, arthralgia, risen disposition to perspire, hepatosplenomegaly. It was revealed, that the level of pro-inflammatory interleukins considerably prevailed over the level of anti-inflammatory ones. Despite the high sensitivity of PCR diagnostics, the positive results in our research were received only in one third of patients.

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Author Biography

Elchin Mammad oglu Huseynov, Azerbaijan Medical University

Department of Infectious Diseases

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Published
2016-11-28
How to Cite
Huseynov, E. M. oglu. (2016). THE FEATURES OF ACUTE BRUCELLOSIS IN AZERBAIJAN REPUBLIC. EUREKA: Health Sciences, (6), 10-15. https://doi.org/10.21303/2504-5679.2016.00208
Section
Medicine and Dentistry