• Igor Galaychuk Ternopil State Medical University
  • Larysa Nitefor Ternopil State Medical University
  • Irina Perepyolkina CSD Health Care Medical Lab
Keywords: breast sarcomas, breast conservative surgery, macromastia


Bilateral breast sarcomas are rare malignancies of unknown etiology. Most common histological subtypes of breast sarcoma are angiosarcoma, fibrosarcoma and malignant fibrous histiocytoma. Phyllodes tumors have a predisposition to transform into sarcoma.

The present clinical case describes bilateral breast fibrosarcomas in a 39 years-old female with macromastia. This peculiarity gave possibilities to do wide local excision of both tumors within 3.0 cmresection margins and preserve both breasts. Histological and immunohistochemical (ERG, CK-AE1/AE3) examination confirmed fibrosarcomas in both breast (in right – stage IIB, in left – stage IIA). Patient carried on postoperative treatment with radiation therapy (36.1 Gy for both breasts) and four cycles of adjuvant chemotherapy (doxorubicin, cisplatin, cyclophosphamide).

For the first year patient had clinical and ultrasound examination every three months, then every 6 months. CT scan of chest and abdomen was every year. In seven post-op years there was no evidence of disease recurrence.

Thus, macromastia gives an exceptional chance to carry out organ-sparing radical surgery in women with advanced breast malignancies.


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Author Biographies

Igor Galaychuk, Ternopil State Medical University

Department of Oncology and Radiology

Larysa Nitefor, Ternopil State Medical University

Department of Oncology and Radiology


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How to Cite
Galaychuk, I., Nitefor, L., & Perepyolkina, I. (2017). BILATERAL BREAST SARCOMA IN WOMEN WITH MACROMASTIA. EUREKA: Health Sciences, (4), 49-54.
Medicine and Dentistry