EUREKA: Health Sciences <p><strong>EUREKA: Health Sciences</strong>&nbsp;– scientific journal, whose main aim is to publish materials focused on ways to preserve health, prevent diseases, technologies and means of treatment of diseases and the use of synthetic drugs. A distinctive feature of the manuscripts submitted to the journal is a component that allows see&nbsp;<strong><em>the new discoveries in the field of health preservation, involving knowledge of the different branches of science.</em></strong></p> Scientific Route OÜ en-US EUREKA: Health Sciences 2504-5660 <p>Our journal abides by the <a href="" target="_blank" rel="noopener">Creative Commons CC BY</a> copyright rights and permissions for open access journals.</p> <p>Authors, who are published in this journal, agree to the following conditions:</p> <p>1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a <a href="" target="_blank" rel="noopener">Creative Commons CC BY</a>, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.</p> <p>&nbsp;2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.</p> Retrospective study of Ct brain imaging findings indicated for infants at a tertiary care hospital <p>Computed tomography in the diagnosis of pathologies in children is becoming increasingly popular.</p> <p>The aim: to study findings of referrals for CT scans (Computerised Tomography) of the brain in children in the department of Radiology in a developing environment.</p> <p><strong>Materials and methods</strong>: retrospective imaging observational study was done in a 1000 bedded tertiary care hospital in South India in the year 2022 from April to August for 5 months under 16 slice CT scan. Cases are referred from the department of Pediatrics to the department of Radiology as part of the routine clinical evaluation and treatment protocol.</p> <p><strong>Results</strong>: Our sample includes 100 infants; after exclusion criteria total of 60 infants' brain CTs were taken into account, and analysed their imaging from radiology department records. Of 60 cases, 18 (30 %) showed HIE Pattern, and 42 (70 %) had normal plain CT Brain findings. However, due to clinical signs and symptoms, they are evaluated under сontrast CT imaging (after checking creatinine levels), showing 20 cases (33.3 %) are standard, 10 cases (16.6 %) show meningitis, and 2 cases (3.3 %) show SOL. Out of 18 cases of HIE, 10 cases (16.6 %) are under less than 6 months and they undergone neuro sonogram showing 4 cases (6.6 %) normal NSG, 2 cases (3.3 %) showing grade IV HIE, another 2 cases (3.3 %) showing grade II, III HIE Findings.</p> <p><strong>Conclusions:</strong> Our study concluded that plain CT brain showed normal in the majority of the cases which came to the department of Radiology after admission to the hospital. Those cases with strong clinical history are evaluated with contrast CT and evaluated the findings. After contrast imaging, most cases showing their infective, obstructive, and other causes of illness are interpreted. However, its role is minimal for seizures in which CT/CECT shows normal study. Under 6 months, NSG is a suitable method for evaluating and screening the infant's brain.</p> Arelly Jyostna Talluri Sunitha Athkuri Ravi Teja Vijaya Kumari M. Ashwini Jyothi A. J. Sunil Kumar P. Copyright (c) 2022 Arelly Jyostna, Talluri Sunitha, Athkuri Ravi Teja, Vijaya Kumari M., Ashwini Jyothi A. J., Sunil Kumar P. 2022-11-30 2022-11-30 6 3 9 10.21303/2504-5679.2022.002717 Prevention of gastrointestinal diseases in piglets at weaning using probiotics Bacillus coagylans and Bacillus megaterium <p><strong>The aim of the study</strong> is to determine the preventive effect of the use of probiotics <em>Bacillus coagulans</em> and <em>Bacillus megaterium</em> in case of gastrointestinal diseases in piglets and as a potential strategy to reduce the misuse of antibiotics in monogastric animals by adding probiotics to the diet of pregnant sows and piglets in the period before and after weaning.</p> <p><strong>Materials and methods. </strong>Three research groups were formed to study the preventive effect of probiotics of the genus <em>Bacillus coagulans</em> and <em>Bacillus megaterium</em>. The piglets of the first experimental group received probiotics at the rate of 0.4 kg per 1 ton of feed in the periods before and after weaning, and that is, the moment of the entire study, the second experimental group received probiotics in the period after weaning, before that they received milk from the sow. The third group was the control group, which received only milk from the sow, and fodder during the weaning period. The effectiveness of the prevention result was determined by the absence/presence of clinical signs of morbidity and % survival of animals during the study period.</p> <p><strong>The results.</strong> It was established that the preservation of livestock in the 1st experimental group was 90 %, and in the 2nd group – 70 %, and control – 50 %.</p> <p><strong>Conclusions.</strong> Research results show that probiotics of the genus <em>Bacillus coagulans</em> and <em>Bacillus megaterium</em>, the components of which provide a wide spectrum of antimicrobial activity, are a reliable preventive measure for gastrointestinal diseases in piglets.</p> Yuliia Bakun Copyright (c) 2022 Yuliia Bakun 2022-11-30 2022-11-30 6 10 14 10.21303/2504-5679.2022.002718 A comparative study of second trimester termination of pregnancy with mifepristone and misoprostol vs misoprostol alone in 50 cases <p><strong>The aim</strong>: To study the efficacy and safety of combined mifepristone and misoprostol used in second-trimester abortion(≥ 12 and ≤ 20 weeks) in comparison with only vaginal misoprostol.</p> <p><strong>Materials and methods: </strong>This study was a prospective comparative randomised clinical study in women attending hospitals in need of a second-trimester abortion, i.e., 12–20 weeks of pregnancy were taken up and divided as Group A – 50 women with mifeprisptone and misoprostol, Group B – 50 women with misoprostol alone Results were analysed according to age, parity, gestational age, average dose of misoprostol required for complete abortion, Induction abortion interval, completeness of abortion, side effects and mean days of hospital stay.</p> <p><strong>Results: </strong>Demographic details are comparable and insignificant in the comparison. The average dose of misoprostol (mcg) required for the completeness of abortion in group A is 596±28.28 mcg, and in group B, it is 1148±160.66 mcg (p&lt;0.001) which is statistically significant. In the present study, the induction abortion interval is significantly less in group A compared to group B, with p&lt;0.001. In addition, 10 out of 50 patients in group A aborted within 7 hours, whereas none in group B. Mean duration of hospital stay in group A is 24 hours. In group B, it is 34.82 hours which is statistically significant with a p-value of &lt;0.001. 12 patients in group A and 26 in group B had side effects like nausea, vomiting, fever, headache and diarrhoea. 8 % of group A and 20 % of group B had a fever. These patients were treated with antipyretics. 6 % in group A and 14 % in group B had nausea and vomiting and were treated with antiemetics. 4 % in group A and 8 % in group B had diarrhoea and were treated with antimotility drugs. 6 % in group A and 10 % in group B had a headache; these patients were treated with NSAIDs.</p> <p><strong>Conclusions: </strong>The combination of mifepristone and misoprostol is a highly effective and safe method for second-trimester termination of pregnancy. The amount of misoprostol needed to accomplish the abortion, and the severity of the adverse effects are lower in the mifepristone-primed group than in the misoprostol-alone group. Since there are fewer difficulties, this approach can be employed in hospitals with high patient density.</p> Maloth Swathi Ratnam Andallu Manekar Balasaraswathi Vederay Suvarna Copyright (c) 2022 Maloth Swathi, Ratnam Andallu, Manekar Balasaraswathi, Vederay Suvarna 2022-11-30 2022-11-30 6 15 22 10.21303/2504-5679.2022.002726 Cross-sectional study to evaluate various cardiovascular manifestations in pregnant women with preeclampsia using 2d echocardiogram <p>Preeclampsia is one of the most frequent complications found in pregnancy. Preeclampsia was initially thought to cause poor long-term cardiovascular outcomes, but recent studies have shown its effect to be more early and severe.</p> <p><strong>Aims</strong>: To reduce the morbidity and mortality for all patients with hypertension in pregnancy through any cardiovascular problem that is directly caused by hypertension in pregnancy</p> <p><strong>Methods</strong>: it is a cross-sectional and observational study of pregnant women with preeclampsia in the reproductive age group (15–44 years) diagnosed with preeclampsia in the antenatal ward/HDU/MICU at Niloufer hospital were evaluated with 2d echo on diagnosis and a follow up 2d echo after delivery was done and changes in 2d echo were noted, patients with prior changes in 2d echo have been excluded from the study. About 113 preeclamptic patients were studied and further classified as non-severe and severe preeclampsia, and their results were compared.</p> <p><strong>Results: </strong>This study shows significant cardiovascular dynamics changes in subjects with preeclampsia (both severe and non-severe) which can be studied by 2 D echo. Non-severe preeclampsia was associated with more normal birth weight. This was found statistically significant in our study. IUD and early neonatal death were more associated with severe preeclampsia when compared to non-severe preeclampsia, which was found statistically significant.</p> <p><strong>Conclusions: </strong>Early identification of preeclamptic patients at higher risk of developing cardiovascular complications later in life by undergoing timely echocardiography.</p> Lakshmi Devi Preet Banerjee D. V. K. Durga Pooja Sahu Copyright (c) 2022 Lakshmi Devi, Preet Banerjee, D. V. K. Durga, Pooja Sahu 2022-11-30 2022-11-30 6 23 30 10.21303/2504-5679.2022.002727 Modern concepts of teeth whitening – a narrative review <p>Whitening has been known since Biblical times. Nowadays, in the developed world, patients are placing a stronger interest in the aesthetic appearance of their teeth. As a result, public demand for aesthetic dentistry, including tooth whitening, has recently increased. Aesthetics of the teeth is of great importance to many patients.</p> <p><strong>The aim is</strong> to summarise and discuss the teeth whitening procedure, tools, materials, and methods, as well as its efficacy and safety. In addition, the paper aims to provide full and comprehensive information for dentists and their patients about the merits and perils of whitening.</p> <p><strong>Methods.</strong> Relevant literature from Scopus published in English was selected using the following search criteria "tooth OR teeth AND whitening OR bleaching" by 2022. In total, there were found 3840 papers. Then, we applied the inclusion and exclusion criteria to the selected scientific papers to choose the relevant ones.</p> <p><strong>Results.</strong> A comprehensive study of the available information related to means and products for teeth whitening was carried out. Whitening may be accomplished by the physical removal of the stain or a chemical reaction to lighten the tooth colour. The indications for appropriate use of tooth-whitening methods and products depend on the correct diagnosis of the discolouration. When used appropriately, tooth-whitening methods are safe and effective.</p> <p><strong>Conclusions.</strong> Tooth whitening is a form of dental treatment and should be completed as part of a comprehensive treatment plan developed by a dentist after an oral examination.</p> Svitlana Boitsaniuk Orest Kochan Mariana Levkiv Copyright (c) 2022 Svitlana Boitsaniuk, Orest Kochan, Mariana Levkiv 2022-11-30 2022-11-30 6 31 43 10.21303/2504-5679.2022.002690 Relationship between maternal abo blood group and rh typing with maternal and perinatal outcome <p>The ABO blood group type has been considered an independent risk factor in pregnancy-related complications leading to significant morbidity and mortality in pregnant mothers and neonates.</p> <p><strong>Aim</strong>: To study the relationship between maternal ABO blood group and Rh typing with maternal and perinatal outcomes.</p> <p><strong>Materials and methods</strong>: Prospective Observational study was carried out for 24 months from November among 1000 pregnant women attending outpatient for ABO blood group and Rh typing with maternal and perinatal outcome.</p> <p><strong>Results</strong>: Among 1000 subjects, 43.5 % belonged to blood group O, followed by 30 % in blood group B. 20.7 % had blood group A, and 5.8 % had AB blood group. In the present study, 95.4 % had Rh+ve, and 4.6 % had Rh-ve typing. The incidence of preterm labour was high at 6.3 % in the O+ve blood group, followed by 1.8 % in the AB +ve, 0.6 % in the A+ve and 0.3 % in the B+ve blood group. A statistically significant association was found between blood grouping and preeclampsia with high incidence among the A+ve blood group. A statistically significant association was found between blood grouping and imminent eclampsia with high incidence among the AB+ve blood group. There was a statistically significant association found between blood grouping and intrauterine death.</p> <p><strong>Conclusion</strong>: The findings in the present study will help clinicians to identify the patients at risk of developing adverse pregnancy outcomes like preeclampsia and imminent eclampsia; hence, the timely intervention will help to improve maternal and perinatal outcome and also helps to reduce the complications of preeclampsia and imminent eclampsia.</p> Arukonda Niranjani Devi Manjula Pathri Sruthi Tammala Copyright (c) 2022 Arukonda Niranjani Devi, Manjula Pathri, Sruthi Tammala 2022-11-30 2022-11-30 6 44 54 10.21303/2504-5679.2022.002723