@article{Vdovichenko_Bober_Lubkovska_Strakhovetskyi_2021, title={UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION}, url={http://journal.eu-jr.eu/sciencerise/article/view/1680}, DOI={10.21303/2313-8416.2021.001680}, abstractNote={<p><strong>The object of the study:</strong> Uterine fibroids (UF) in women of early reproductive age.</p> <p><strong>The problem to be solved:</strong> Improving the effectiveness of postoperative rehabilitation in women of early reproductive age with uterine fibroids based on the study of its morphological features and improvement of rehabilitation measures.</p> <p><strong>The main scientific results:</strong> It was found that in women of early reproductive age with UF the most common complaints are posthemorrhagic anemia (61.0 %, or 61 women). Regarding the menstrual cycle, the most common dysmenorrhea โ€“ 26.0 % (in 26 women). The importance of heredity in the development of such pathology in young women (32.0 %, or 32 women) was confirmed. The most common localization of fibroids is interstitial โ€“ 79.0 % (in 79 women).</p> <p>Morphological study found that women of early reproductive age most often have a simple UF, namely 96 % (96 women). Uterine leiomyoma was present in 56 % (56 women).</p> <p>A study of the hormonal status of women of early reproductive age found that the mean values โ€‹โ€‹of hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, prolactin and testosterone were higher before surgery than after. When comparing rehabilitation methods (combined oral contraceptives (COCs) or gonadotropin-releasing hormone agonists (GnRH agonists), it was found that postoperative rehabilitation by using COCs for 6-12 months provides significantly better indicators of recovery of hormonal status, indicating the effectiveness of rehabilitation method.</p> <p><strong>Scope of practical application of research results:</strong> Practical medicine specializing in the diagnosis, treatment and prevention of recurrence of uterine fibroids.</p> <p><strong>Innovative technological product:</strong> Improved algorithm of postoperative rehabilitation measures by applying COC for 6-12 months after myomectomy, which provides significantly better results in restoring hormonal status during rehabilitation.</p> <p><strong>Scope of application of innovative technological product:</strong> clinical medical practice related to the diagnosis, treatment and prevention of recurrence of uterine fibroids.</p&gt;}, number={1}, journal={ScienceRise}, author={Vdovichenko, Serhii and Bober, Anna and Lubkovska, Oleksandra and Strakhovetskyi, Vitalii}, year={2021}, month={Feb.}, pages={55-61} }