• Yuri Vinnyk Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
  • Vadym Vlasenko Medical Center "Molecule"
  • Anna Baranova Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
Keywords: breast cancer, radical surgery, lymph node dissection, complications


Breast cancer is one of the most common malignancies in women. In many cases, a major component of complex treatment for breast cancer is surgery - radical mastectomy or radical breast resection.

The aim of the work – to investigate the frequency and structure of complications after radical surgery with dissection of axillary lymph nodes in breast cancer patients.

Material and methods. The baseline and surgical results of 147 women with breast cancer who underwent radical mastectomy or radical breast resection with lymph node dissection were analysed.

Results. Complications in the early period after surgery for breast cancer were found in 76 (51.7 %), including postoperative extremity edema in 60 (40.8 %); lymphorrhea – in 37 (25.2 %), seroma – in 33 (22.4 %); wound infection in 18 (12.2 %), necrosis of the wound edges – in 15 (10.2 %) patients. Correlation of postoperative edema with almost all other complications was found, lymphorrhea and seroma were most associated with swelling and with each other; necrosis of edges with postoperative edema. Wound infection was significantly associated with lymphorrhea. Patients' age, stage of disease, and immunohistochemical type of tumour did not affect the development of complications. With increasing BMI, the incidence of complications increased significantly (χ2=9.530; p=0.009). The tendency to decrease the frequency of complications during reconstructive surgery was revealed (42.6 % versus 58.1 %, p=0.064), and adjuvant radiotherapy, on the contrary, contributed to the increase of complications (57.8 % versus 43.8 %, p=0.090).

Conclusion. Radical operations with lymph node dissection in patients with breast cancer are characterized by a high frequency of early postoperative complications, mainly associated with disorders of lymphatic outflow, which indicates the need for a set of measures of preoperative preparation, improvement of surgical technique


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Author Biographies

Yuri Vinnyk, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine

Department of cancer surgery, radiation therapy and palliative care

Vadym Vlasenko, Medical Center "Molecule"

Department of cancer surgery

Anna Baranova, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine

Department of cancer surgery, radiation therapy and palliative care


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How to Cite
Vinnyk, Y., Vlasenko, V., & Baranova, A. (2020). EARLY COMPLICATIONS AFTER RADICAL OPERATIONS IN BREAST CANCER PATIENTS. EUREKA: Health Sciences, (1), 3-9. https://doi.org/10.21303/2504-5679.2020.001119
Medicine and Dentistry