Optimization of treatment and prevention of generalized periodontal diseases with the use of transgingival photoactived disinfection
The aim of the study is to develop protocols for the treatment and prevention of generalized periodontal disease using a nozzle that designed for transgingival photosensitizer activation.
Methods. Analysis of available variants of irradiation nozzles for photoactivated disinfection. Circuit design and construction of authors’ irradiation nozzle for transgingival photosensitizer activation.
Results. Based on the analysis of data, there was developed a nozzle design that allows treating periodontium areas within 4-6 teeth, evenly distributes the required power of laser radiation, and can be used in hard-to-reach areas of the oral cavity. Based on the above calculations, a nozzle for transgingival photosensitizer activation was created (jointly with Fotonika Plus, PE). To optimize the PAD procedure, there was created a protocol of transgingival photoactivated disinfection to be applied at the stage of professional oral hygiene, using the created irradiation nozzle NOU-9 of authors’ design, and diode 2 W laser LIKA-surgeon with a wavelength of 660 nm. The result is the accelerated procedure of transgingival photoactivated disinfection.
Conclusions. The development of photoactivated disinfection technology allows supplementing the traditional treatment of generalized periodontal diseases. Studies of non-invasive, transgingival method of photosensitizer activation have recently become popular. This, in turn, carries a lower probability of cross-infection and less traumatization of periodontal tissues during the manipulation. The use of PAD cannot lead to resistance of the microflora in contrast to pharmacological antibacterial preparations. Carrying out PAD does not require any complex manual skills, the purchase of expensive equipment, provides an opportunity for widespread introduction of technology. The use of the therapeutic complex and protocols of PAD that were developed can significantly reduce the duration of the procedure, resulting in improved comfort for both the doctor and the patient. The NOU-9 irradiation nozzle allows reaching hard-to-reach areas of the oral cavity, distributing laser radiation efficiently and evenly on periodontal tissues. The LIKA-surgeon 2 W laser with a wavelength of 660 nm provides the operating parameters required to activate the photosensitizer. Due to low-intensity radiation, it is possible to enhance regenerative processes in the periodontium after traumatic intervention. Clinical studies on the antibacterial efficacy of the technology are ongoing
Nazir, M. A. (2017). Prevalence of periodontal disease, its association with systemic diseases and prevention. International Journal of Health Sciences, 11 (2), 72–80.
Mazur, I. P., Peredrii, V. A., Dulko, S. V. (2010). Pharmacological chemicals for the local treatment of periodontal tissues. Parodontolohiia, 5, 47–52.
Kampf, G. (2016). Acquired resistance to chlorhexidine – is it time to establish an “antiseptic stewardship” initiative? Journal of Hospital Infection, 94 (3), 213–227. doi: http://doi.org/10.1016/j.jhin.2016.08.018
Rams, T. E., Degener, J. E., van Winkelhoff, A. J. (2014). Antibiotic Resistance in Human Chronic Periodontitis Microbiota. Journal of Periodontology, 85 (1), 160–169. doi: http://doi.org/10.1902/jop.2013.130142
Coovadia, Y., Vayej, A. C., Maharaj, B. (2012). An investigation of the frequency of bacteraemia following dental extraction, tooth brushing and chewing: cardiovascular topics. Cardiovascular Journal of Africa, 23 (6), 340–344. doi: http://doi.org/10.5830/cvja-2012-016
Parker, S. (2013). The use of diffuse laser photonic energy and indocyanine green photosensitiser as an adjunct to periodontal therapy. British Dental Journal, 215 (4), 167–171. doi: http://doi.org/10.1038/sj.bdj.2013.790
Novaes, A. B., Schwartz-Filho, H. O., de Oliveira, R. R., Feres, M., Sato, S., Figueiredo, L. C. (2011). Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: microbiological profile. Lasers in Medical Science, 27 (2), 389–395. doi: http://doi.org/10.1007/s10103-011-0901-6
Obradović, R., Kesić, L., Mihailović, D., Antić, S., Jovanović, G., Petrović, A., Peševska, S. (2012). A histological evaluation of a low-level laser therapy as an adjunct to periodontal therapy in patients with diabetes mellitus. Lasers in Medical Science, 28 (1), 19–24. doi: http://doi.org/10.1007/s10103-012-1058-7
Passanezi, E., Damante, C. A., de Rezende, M. L. R., Greghi, S. L. A. (2014). Lasers in periodontal therapy. Periodontology 2000, 67 (1), 268–291. doi: http://doi.org/10.1111/prd.12067
Husejnagic, S., Lettner, S., Laky, M., Georgopoulos, A., Moritz, A., Rausch‐Fan, X. (2019). Photoactivated disinfection in periodontal treatment: A randomized controlled clinical split‐mouth trial. Journal of Periodontology, 90 (11), 1260–1269. doi: http://doi.org/10.1002/jper.18-0576
Wenzler, J. S., Böcher, S., Frankenberger, R., Braun, A. (2019). Feasibility of transgingival laser irradiation for antimicrobial photodynamic therapy. Photodiagnosis and Photodynamic Therapy, 28, 75–79. doi: http://doi.org/10.1016/j.pdpdt.2019.08.030
Ronay, V., Buchalla, W., Sahrmann, P., Attin, T., Schmidlin, P. R. (2013). In vitroevaluation of the oxidation efficacy of transgingival photodynamic therapy. Acta Odontologica Scandinavica, 71 (5), 1216–1220. doi: http://doi.org/10.3109/00016357.2012.757639
Chatzopoulos, G. S., Doufexi, A. E. (2016). Photodynamic therapy in the treatment of aggressive periodontitis: A systematic review. Medicina oral, patologia oral y cirugia bucal, 21 (2), e192–e200. doi: http://doi.org/10.4317/medoral.21046
Copyright (c) 2021 Valerii Burhonskyi, Sviatoslav Mykolaichuk, Valeriy Voitsekhovych, Vladimir Kholin , Anna Reva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.