Association of psychological status with first diagnosed pulmonary tuberculosis in men
The aim. Assessment of the initial psychological status of men with first diagnosed pulmonary tuberculosis and the study of its associations with the clinical course of the disease.
Materials and methods. The study involved 54 men with first diagnosed pulmonary tuberculosis. Patients had a dynamic complex clinical, laboratory and instrumental examination with an assessment of the psychological status according to the State-Trait Anxiety Inventory (STAI) and the Beck Depression Inventory (BDI).
Results. The evaluating of initial psychological status in patients with first diagnosed pulmonary tuberculosis, depressive states of varying severity were found in 47.05 % of patients, moderate state anxiety – in 74.51 % of patients, moderate trait anxiety – in 35.29 %. We revealed associations of the levels of anxiety and depression with the degree of bacterial excretion and the duration of the intensive phase of therapy.
Conclusions. To assess the psychological status of patients with first diagnosed infiltrative pulmonary tuberculosis, it is advisable to use the STAI and the BDI.
Patients with first diagnosed infiltrative pulmonary tuberculosis in 100 % of cases have psychological status disorders with a predominance of moderate state anxiety and the absence of depressive disorders in only half of them. More expressed violations of the psychological status (anxiety, depression) identifies patients who are married and have a steady job.
In patients with first diagnosed infiltrative pulmonary tuberculosis, an increase in the severity of anxiety and depression is associated with more expressed bacterial excretion, decrease in body weight, greater frequency of destruction of lung tissue, prevalence of the tuberculosis process by more than 2 lung segments, decrease in the effectiveness of standard therapy and prolongation intensive phase of treatment.
Global Tuberculosis Report (2020). World Health Organization. Licence: CC BY-NC-SA 3.0 IGO. Geneva, 232.
Pezzella, A. T. (2019). History of Pulmonary Tuberculosis. Thoracic Surgery Clinics, 29 (1), 1–17. doi: http://doi.org/10.1016/j.thorsurg.2018.09.002
Courtwright, A., Turner, A. N. (2010). Tuberculosis and Stigmatization: Pathways and Interventions. Public Health Reports, 125 (4_suppl), 34–42. doi: http://doi.org/10.1177/00333549101250s407
Shrestha, S. K., Joshi, S., Bhattarai, R. B., Joshi, L. R., Adhikari, N., Shrestha, S. K. et. al. (2020). Prevalence and risk factors of depression in patients with drug-resistant tuberculosis in Nepal: A cross-sectional study. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 21, 100200. doi: http://doi.org/10.1016/j.jctube.2020.100200
Dasa, T. T., Roba, A. A., Weldegebreal, F., Mesfin, F., Asfaw, A., Mitiku, H. et. al. (2019). Prevalence and associated factors of depression among tuberculosis patients in Eastern Ethiopia. BMC Psychiatry, 19 (1). doi: http://doi.org/10.1186/s12888-019-2042-6
Cho, I. Y., Chang, Y., Sung, E., Sohn, W., Kang, J.-H., Shin, H., Ryu, S. (2020). Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study. Scientific Reports, 10 (1). doi: http://doi.org/10.1038/s41598-020-77886-2
Iftikhar, A., Islam, M., Shepherd, S., Jones, S., Ellis, I. (2021). Cancer and Stress: Does It Make a Difference to the Patient When These Two Challenges Collide? Cancers, 13 (2), 163. doi: http://doi.org/10.3390/cancers13020163
Ehrt, S., Schnappinger, D., & Rhee, K. Y. (2018). Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis. Nature Reviews Microbiology, 16 (8), 496–507. doi: http://doi.org/10.1038/s41579-018-0013-4
Dean, A. S., Cox, H., Zignol, M. (2017). Epidemiology of Drug-Resistant Tuberculosis. Strain Variation in the Mycobacterium Tuberculosis Complex: Its Role in Biology, Epidemiology and Control, 209–220. doi: http://doi.org/10.1007/978-3-319-64371-7_11
Depression and Other Common Mental Disorders: Global Health Estimates (2017). World Health Organization. Available at: http://www.jstor.org/stable/resrep28026.1 Last accessed: 22.04.2021
Picco, L., Subramaniam, M., Abdin, E., Vaingankar, J., Chong, S. (2017). Gender differences in major depressive disorder: findings from the Singapore Mental Health Study. Singapore Medical Journal, 58 (11), 649–655. doi: http://doi.org/10.11622/smedj.2016144
Sweetland, A., Oquendo, M., Wickramaratne, P., Weissman, M., Wainberg, M. (2014). Depression: a silent driver of the global tuberculosis epidemic. World Psychiatry, 13 (3), 325–326. doi: http://doi.org/10.1002/wps.20134
Pardal, P., Singh, L., Prakash, J. (2015). Psychiatric morbidity in patients of pulmonary tuberculosis-an observational study. Industrial Psychiatry Journal, 24 (2), 168. doi: http://doi.org/10.4103/0972-6748.181722
Wood, A. M., Boyce, C. J., Moore, S. C., Brown, G. D. A. (2012). An evolutionary based social rank explanation of why low income predicts mental distress: A 17 year cohort study of 30,000 people. Journal of Affective Disorders, 136 (3), 882–888. doi: http://doi.org/10.1016/j.jad.2011.09.014
Peltzer, K., Naidoo, P., Matseke, G., Louw, J., Mchunu, G., Tutshana, B. (2012). Prevalence of psychological distress and associated factors in tuberculosis patients in public primary care clinics in South Africa. BMC Psychiatry, 12 (1). doi: http://doi.org/10.1186/1471-244x-12-89
Katon W. J. (2011). Epidemiology and treatment of depression in patients with chronic medical illness. Dialogues in clinical neuroscience, 13 (1), 7–23. doi: http://doi.org/10.31887/dcns.2011.13.1/wkaton
Almeida, S. S., Zizzi, F. B., Cattaneo, A., Comandini, A., Di Dato, G., Lubrano, E. et. al. (2020). Management and Treatment of Patients With Major Depressive Disorder and Chronic Diseases: A Multidisciplinary Approach. Frontiers in Psychology, 11. doi: http://doi.org/10.3389/fpsyg.2020.542444
Spielberger, C. D., Gorsuch, R. L., Lushene, R. Vagg, P. R., Jacobs, G. A. (1983). Manual for the State-Trait Anxiety Inventory. Palo Alto: Consulting Psychologists Press.
Karelin, A. (2007). Great Encyclopedia of Psychological Tests. Moscow: “Eksmo” Publishing House, 416.
Beck, A. T., Steer, R. A., Carbin, M. G. (1988). Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clinical Psychology Review, 8 (1), 77–100. doi: http://doi.org/10.1016/0272-7358(88)90050-5
Duko, B., Gebeyehu, A., Ayano, G. (2015). Prevalence and correlates of depression and anxiety among patients with tuberculosis at WolaitaSodo University Hospital and Sodo Health Center, WolaitaSodo, South Ethiopia, Cross sectional study. BMC Psychiatry, 15 (1). doi: http://doi.org/10.1186/s12888-015-0598-3
Aamir, S., Aisha (2010). Co-morbid anxiety and depression among pulmonary tuberculosis patients. Journal of the College of Physicians and Surgeons – Pakistan, 20 (10), 703–704.
Tola, H. H., Shojaeizadeh, D., Garmaroudi, G., Tol, A., Yekaninejad, M. S., Ejeta, L. T. et. al. (2015). Psychological distress and its effect on tuberculosis treatment outcomes in Ethiopia. Global Health Action, 8 (1), 29019. doi: http://doi.org/10.3402/gha.v8.29019
Ruiz-Grosso, P., Cachay, R., de la Flor, A., Schwalb, A., Ugarte-Gil, C. (2020). Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis. PLOS ONE, 15 (1), e0227472. doi: http://doi.org/10.1371/journal.pone.0227472
Chandra, M., Rana, P., Chandra, K., Arora, V. K. (2019). Tuberculosis – Depression syndemic: A public health challenge. Indian Journal of Tuberculosis, 66 (1), 197–202. doi: http://doi.org/10.1016/j.ijtb.2019.02.007
Copyright (c) 2021 Maryna Koсhuieva, Vasyl Kushnir, Ivan Hrek
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.