Features of retrochoir hematomas and their effect on the course of pregnancy
Abstract
The aim. Study of the features of retrochoir hematomas (RHG) and their influence on the formation of the placenta, the course of pregnancy, as well as the occurrence of premature birth.
Materials and methods. 2 groups of pregnant women were selected depending on the frequency of RHG formation: 1 group – 60 pregnant women with recurrent RHG, group 2 – 50 pregnant women with RHG, which was detected only in the early stages of pregnancy. extragenital and genital pathology did not differ reliably. All the women studied were anamnesis, examined, and ultrasound and dopplerometry were performed.
Statistical methods included an assessment of statistical significance using Student's t-criterion and criterion X2 and were considered significant at p<0.05.
Results. Supracervical localization of hematomas prevailed in the studied pregnant women, namely: in group 1 – 51.7 % (in 31 pregnant women) and 68 % (in 34 women) in group 2. The same pattern was observed regarding the involution of hematomas.
Changes in the yolk sac were found in both groups with RHG (in 6.7 % of women (i.e., in 4 pregnant women) of group 1 and 4 % (in 2 pregnant women) of group 1.
Mean values of the pulsation index (PI) of blood flow velocity curves in the uterine arteries (UA) and umbilical cord artery (UCA) in pregnant women with RHG were higher than the standard average for gestational age.
In pregnant RHGs, a history of various types of fetal growth retardation (FGR) is detected. The number of early forms of URP was higher in group 1 (16.7 %, i.e. in 10 pregnant women) as opposed to group 2 (2.0 %, i.e. 1 case). The late form was approximately the same amount in both groups. Also, group 1 was characterized by a significantly larger number of FGR of 2-3 centuries.
In addition, in both groups with RHG, such pathological conditions were identified during pregnancy as the threat of premature birth, premature placental maturation, placental hypoplasia, oligohydramnios, and hydramnios.
Conclusions. Pregnant women with recurrent RHG compared to pregnant women with sporadic RHGs have a greater number of complications during pregnancy, including the threat of preterm labour, premature placental maturation, placental hypoplasia, oligohydramnios, hydramnios, FGR, impaired uterine-placental and placental-fetal blood flow.
Downloads
References
Soldo, V., Cutura, N., Zamurovic, M. (2013). Threatened miscarriage in the first trimester and retrochorial hematomas: sonographic evaluation and significance. Clinical and Experimental Obstetrics & Gynecology, 40 (4), 548–550.
Shi, X., Du, L., Su, Q., Tian, Y. (2019). Comparative study of clinical features and pregnancy outcomes of intrauterine subchorionic hematoma and retroplacental hematoma. Chinese Journal of Postgraduates of Medicine, 36, 900–903.
Li, Y., Wang, E., Huang, S., Zhu, C., Zhang, K., Zhang, J. et. al. (2021). Autoantibodies in association with subchorionic haematoma in early pregnancy. Annals of Medicine, 53 (1), 841–847. doi: http://doi.org/10.1080/07853890.2021.1936150
Sultangadzhieva, K. G., Khizroeva, J. K. (2020). Pathogenetically differentiated management of pregnancy in patients with retrochorial hematoma. Obstetrics, Gynecology and Reproduction, 14 (1), 15–24. doi: http://doi.org/10.17749/2313-7347.2020.14.1.15-24
Milovanov, A. P., Kuznetsova, N. B., Bushtyreva, I. O. (2016). The morphology, typical combinations of polymorphic genes of hemostasis, and specific features of the pathogenesis of retrochorial hematoma in missed abortion. Arkhiv Patologii, 78 (5), 3–8. doi: http://doi.org/10.17116/patol20167853-8
Orujova, P. F., Shamhalova, I. A. (2018). Sonographic parameters in women with retrochorial hematoma in the I Trimester of pregnancy. Azerbaidzhanskyi medytsynskyi zhurnal, 1, 55–60.
Lisova, K. M., Kalinovska, I., Tokar, P. (2022). Ultrasound characteristic of embryo, fetal egg and chorionic structures in pregnant women with miscarriage. Wiadomości Lekarskie, 75 (1), 75–78. doi: http://doi.org/10.36740/wlek202201114
Heller, H. T., Asch, E. A., Durfee, S. M., Goldenson, R. P., Peters, H. E., Ginsburg, E. S. et. al. (2018). Subchorionic Hematoma: Correlation of Grading Techniques With First‐Trimester Pregnancy Outcome. Journal of Ultrasound in Medicine, 37 (7), 1725–1732. doi: http://doi.org/10.1002/jum.14524
Sukur, Y. E., Goc, G., Kose, O., Acmaz, G., Ozmen, B., Atabekoglu, C. S. et. al. (2014). The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion. Journal of the Turkish German Gynecological Association, 15 (4), 239–242. doi: http://doi.org/10.5152/jtgga.2014.14170
Ott, J., Pecnik, P., Promberger, R., Pils, S., Binder, J., Chalubinski, K. M. (2017). Intra- versus retroplacental hematomas: a retrospective case-control study on pregnancy outcomes. BMC Pregnancy and Childbirth, 17 (1). doi: http://doi.org/10.1186/s12884-017-1539-6
Xiang, L., Wei, Z., Cao, Y. (2014). Symptoms of an Intrauterine Hematoma Associated with Pregnancy Complications: A Systematic Review. PLoS ONE, 9 (11), e111676. doi: http://doi.org/10.1371/journal.pone.0111676
Naert, M. N., Muniz Rodriguez, A., Khadraoui, H., Naqvi, M., Fox, N. S. (2019). Association Between First-Trimester Subchorionic Hematomas and Adverse Pregnancy Outcomes After 20 Weeks of Gestation in Singleton Pregnancies. Obstetrics & Gynecology, 134 (4), 863–868. doi: http://doi.org/10.1097/aog.0000000000003487
Karaçor, T., Bülbül, M., Nacar, M. C., Kırıcı, P., Peker, N., Ağaçayak, E. (2019). The effect of vaginal bleeding and non-spesific pelvic pain on pregnancy outcomes in subchorionic hematomas cases. Ginekologia Polska, 90 (11), 656–661. doi: http://doi.org/10.5603/gp.2019.0111
Janowicz-Grelewska, A., Sieroszewski, P. (2013). Prognostic significance of subchorionic hematoma for the course of pregnancy. Polish Gynaecology, 84 (11). doi: http://doi.org/10.17772/gp/1664
Liu, Y., Tong, A., Qi, X. (2020). A large subchorionic hematoma in pregnancy. Medicine, 99 (22), e20280. doi: http://doi.org/10.1097/md.0000000000020280
Hashem, A., Sarsam, S. D. (2018). The Impact of Incidental Ultrasound Finding of Subchorionic and Retroplacental Hematoma in Early Pregnancy. The Journal of Obstetrics and Gynecology of India, 69 (1), 43–49. doi: http://doi.org/10.1007/s13224-017-1072-6
Naert, M. N., Khadraoui, H., Muniz Rodriguez, A., Naqvi, M., Fox, N. S. (2019). Association Between First-Trimester Subchorionic Hematomas and Pregnancy Loss in Singleton Pregnancies. Obstetrics & Gynecology, 134 (2), 276–281. doi: http://doi.org/10.1097/aog.0000000000003360
Kamble, P. D., Bava, A., Shukla, M., Nandanvar, Y. S. (2017). First trimester bleeding and pregnancy outcome. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 6 (4), 1484–1488. doi: http://doi.org/10.18203/2320-1770.ijrcog20171414
Kyser, K. L. (2012). Meta-analysis of subchorionic hemorrhage and adverse pregnancy outcomes. Proceedings in Obstetrics and Gynecology, 2 (4). doi: http://doi.org/10.17077/2154-4751.1137
Tuuli, M. G., Norman, S. M., Odibo, A. O., Macones, G. A., Cahill, A. G. (2011). Perinatal Outcomes in Women With Subchorionic Hematoma. Obstetrics & Gynecology, 117 (5), 1205–1212. doi: http://doi.org/10.1097/aog.0b013e31821568de
Ji, W., Li, W., Mei, S., He, P. (2016). Intrauterine hematomas in the second and third trimesters associated with adverse pregnancy outcomes: a retrospective study. The Journal of Maternal-Fetal & Neonatal Medicine, 30 (18), 2151–2155. doi: http://doi.org/10.1080/14767058.2016.1241762

Copyright (c) 2022 Ilona Koshova, Oleksandra Lubkovska

This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.