CHANGES IN SOME PERIPHERAL BLOOD IMMUNE PARAMETERS OF PATIENTS WITH CHRONIC PERIODONTITIS AMONG SERVICEMEN OF THE ARMED FORCES OF UKRAINE

Keywords: periodontitis, periostitis, immunogram, immune status

Abstract

The object of research: the state of chronic periodontitis among servicemen of the Armed Forces of Ukraine remains extremely urgent. Therefore a group of servicemen with chronic periodontitis and its complications was taken. In addition, a control group of servicemen was used to compare the results.

Investigated problem: in this article, the diagnosis was considered due to the use of immunological studies of peripheral blood of sick servicemen of the Armed Forces of Ukraine with chronic periodontitis, as well as its complications. The study of the features of immunological parameters in peripheral blood was performed.

The main scientific results: according to the obtained data, there is a relative suppression of immunity among servicemen with chronic periapical infection compared with servicemen of the control group.

According to our data, the main lymphocyte subpopulation of peripheral blood are CD8 and CD4 / CD8; CD19+(B-lymphocytes) and CD3-HLA+; CD4 and CD4 / CD8, which reflect inflammatory processes in the body. These indicators are closely interrelated.

The area of practical use of the research results: these results of research can be applied to students’ training at stomatology faculties, in stomatology practice, to research into the immunological status of patients with chronic periodontitis and its complications.

Innovative technological product: it is the first time the study of the immunological status of peripheral blood during chronic periapical infections among servicemen has been performed.

Scope of the innovative technological product: this study can be used in the diagnosis and treatment of chronic periodontitis in dental practice, as well as in the research to compare the results of the immunological state of peripheral blood.

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Author Biography

Anatoliy Gulyuk, Odessa National Medical University

Department of Surgical Dentistry

References

Nikolay, A. S., Sarbayeva, N. N., Dukal'skaya, O. Yu. (2010). Features of the response of the military personnel’s immune system with low neuropsychic stability under the influence of military professional factors. Uchenyye zapiski, 2 (60), 116–118.

Vesna, Ye. A., Gulyuk, A. G. (2018). Biochemical analysis of oral salivary liquid, blood serum and pathologically changed periapical tissue according to inflammation activity parameters in patients with chronic apical periodontitis. Vestnik stomatologii, 3, 15–20.

Kernits'kiy, R. V., Gulyuk, A. G., Goryanova, N. O., Ul'yanov, V. O. (2012). Features of morphofunctional changes in periodontal tissues in chronic periodontitis and periodontitis. Morfologiya, 4, 58–63.

Sevast'yanov, A. V. (2016). Periodontitis. Etiology, pathogenesis, clinical picture, treatment. Saint Petersburg, 40.

Mikhalchenko, V. F., Manuylova, E. V., Yakovlev, A. T. (2012). Dynamics of indices of local immunity in the treatment of chronic periodontitis with the use of calcium-containing drugs. Biology and biotechnology, 1 (3), 37–40.

Kanyura, O. A. (2014). The state of dental health and the need for orthopedic care for patients of a private dental institution. Bulletin of problems of biology and medicine, 4 (2), 279–282.

Yugov, V. K. (2014). X-ray features of changes in periodontitis depending on the form and phase of the process. Radiology of the head and neck. Radiation diagnostics, radiation therapy, 4, 10–19.

Könönen, E., Gursoy, M., Gursoy, U. (2019). Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues. Journal of Clinical Medicine, 8 (8), 1135. doi: http://doi.org/10.3390/jcm8081135

Pashchenkov, M. V., Pinegin, B. V. (2002). The role of dendritic cells in the regulation of the immune response. Immunologiya, 5, 313–321.

Pinegin, B. V., Yarilin, A. A. (2001). Application of flow cytometry to assess the functional activity of the human immune system. Moscow, 53.

Nikolishin, A. (2012). Therapeutic dentistry. Vinnytsia: Nova Kniga, 680.

Jin, L., Söder, B., Corbet, E. F. (2000). Interleukin-8 and Granulocyte Elastase in Gingival Crevicular Fluid in Relation to Periodontopathogens in Untreated Adult Periodontitis. Journal of Periodontology, 71 (6), 929–939. doi: http://doi.org/10.1902/jop.2000.71.6.929

Vasanthakumar, A., Kallies, A. (2015). The Regulatory T Cell: Jack-Of-All-Trades. Trends in Immunology, 36 (12), 756–758. doi: http://doi.org/10.1016/j.it.2015.10.002

Arpaia, N., Green, J. A., Moltedo, B., Arvey, A., Hemmers, S., Yuan, S. et. al. (2015). A Distinct Function of Regulatory T Cells in Tissue Protection. Cell, 162 (5), 1078–1089. doi: http://doi.org/10.1016/j.cell.2015.08.021

Cardoso, E. M., Arosa, F. A. (2017). CD8+T Cells in Chronic Periodontitis: Roles and Rules. Frontiers in Immunology, 8. doi: http://doi.org/10.3389/fimmu.2017.00145


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Published
2020-10-31
How to Cite
Schmidt, P., & Gulyuk, A. (2020). CHANGES IN SOME PERIPHERAL BLOOD IMMUNE PARAMETERS OF PATIENTS WITH CHRONIC PERIODONTITIS AMONG SERVICEMEN OF THE ARMED FORCES OF UKRAINE. ScienceRise, (5), 54-60. https://doi.org/10.21303/2313-8416.2020.001461
Section
Innovative technologies in healthcare